Julian Pacheco

OHSU Vaccine & Gene Therapy Institute
M.S. Data Science, Willamette University
B.S. Biology, Portland State University
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01

Story

I'm a biomedical researcher with more than four years in HIV immunology and nonhuman primate models at OHSU's Vaccine and Gene Therapy Institute. Over that time I came to believe that the bottleneck on discovery was the data itself.

Every new technique we introduced generated more data, faster and at greater complexity, yet I kept watching promising questions stall because no one had the time or tools to explore what we'd already collected. The researchers I learned from saw the same problem from different angles. Dr. Lydie Trautmann first brought me into the field, Dr. Hiroshi Takata mentored me across two labs, and Dr. Afam Okoye leads the group I work with now. Even on strong teams the constraint held: our ability to measure biology had outpaced our ability to analyze it.

So I went after the other half of the toolkit, a master's in data science from Willamette University. There I built public health dashboards and data pipelines, along with statistical and machine learning models of regional affordability. That work taught me to turn large, fragmented datasets into analysis that holds up when someone else questions it or builds on it. I now apply those methods to immunology data, where the questions I care about run in more dimensions than conventional analysis can follow.

My long-term goal is translational: move discoveries from biological measurement to therapeutic development and, eventually, to patients. Immunology is where this started, but my interests run wider: I want to apply that same kind of analysis to new data types and new domains, wherever it's missing. I'll go wherever the hardest open question is.

Immunology
Data Science
Engineering
Public Health
Impact
02

Experience

2021 — Present
Research Assistant
Vaccine and Gene Therapy Institute · OHSU · Beaverton, OR
  • Contributed immune response analysis to a Phase 1b trial of lenacapavir, an FDA Breakthrough Therapy designated regimen now in Phase 2, joining a collaborative effort to bring this lifesaving treatment closer to market.
  • Built and ran multiparameter flow cytometry pipelines across human and NHP models, transforming high dimensional data into quantified results that anchored publications, presentations, and grant reporting.
  • Contributed to a multidisciplinary team designing longitudinal NHP and human studies, building time series data structures (viral load, cytokine, cell associated RNA/DNA) from in vivo and in vitro samples to study how SIV and HIV persist during treatment.
2020
Biological Field Technician
Bureau of Land Management ·(Contract)· Lakeview, OR
  • Built rigorous data collection and integrity practices in the field on a Greater Sage Grouse and juniper removal study, the same foundation of clean, reliable data that drives my work from raw inputs to analysis today.
  • Collected precise field data across a diverse range of instruments and methods, from vegetation and soil sampling to radio telemetry, nest assessments, and brood counts, building the technical versatility I carry across tools and platforms today.
03

Education

2026
M.S., Data Science
Willamette University · Salem, OR
2017
B.S., Biology
Portland State University · Portland, OR
04

Research & Contributions

Click a badge (Poster, Powerpoint, Paper) to view the source.

2026
Takata H, Pacheco J, et al. “RV550: IL-15 Superagonist N-803 at ART Interruption Enhances NK and T Cell Proliferation and Activation Prior to Viral Rebound.” Contributions featured.
Keystone Symposia — HIV Persistence, Remission, and Cure · Breckenridge, CO
Poster
2025
Cai Y, Takata H, Ferreira AM, Pacheco Mendez J, et al. “HIV-Specific T Cell Responses in Suppressed People with HIV-1 Receiving Lenacapavir, Teropavimab, and Zinlirvimab.” Contributions featured.
IAS 2025, Kigali, Rwanda · #OAA0205
Powerpoint
2025
Takata H, Pacheco J, et al. “RV550: IL-15 Superagonist N-803 With ART in Acute HIV Infection Enhances T and NK Cell Proliferation.” Contributions featured.
CROI 2025, San Francisco, CA · #0444
Poster
2025
Varco-Merth B, Marino A, Takata H, Pacheco J, et al. “IL-15 Superagonist at ART Initiation Expands SIV-Specific CD8+ T Cells in Blood and Lymphoid Tissues.” Contributions featured.
CROI 2025, San Francisco, CA · #309
Poster
2023
Takata H, Mitchell JL, Pacheco J, et al. “An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status.”
Cell Host & Microbe, 31(9):1494–1506.e4
Paper
2023
Mitchell J, Subra C, Julian Pacheco, et al. “Compartmentalized Clonal Expansions of CD8+ T Cells in CSF During Acute HIV Infection.” Contributions featured.
CROI 2023 (Virtual)
Poster
05

Toolkit

Data Analytics

  • Longitudinal Regression Analysis
  • Unsupervised Clustering
  • Time Series Analysis
  • Automation Exposure Analysis
  • pandas

Machine Learning

  • Supervised Classification & Regression
  • Feature Extraction & Classification
  • Dimensionality Reduction (PCA, TruncatedSVD)
  • Ensemble Model Optimization
  • Neural N0etwork Architecture
  • scikit-learn
  • TensorFlow

Data Engineering

  • ETL pipeline design (SQLAlchemy, Python)
  • Data modeling for Analytics
  • Pipeline Orchestration & Automation
  • Database Architecture & OptimizationB
  • Apache Airflow
  • dbt
  • DuckDB
  • Databricks

Languages

  • Python
  • R
  • SQL
  • Bash
  • C#

Projects

Tournament Guide World Cup 2026 A hand-built companion guide for the 2026 World Cup, with no template and no CMS. Covers the tournament format and rules, an interactive base-camp map, live group standings, a full FIFA pre-tournament ranking chart for all 48 teams, and match recaps updated through the knockout rounds.
Data Dashboard Beyond the Grid Analyzes whether U.S. states invest in renewable energy proportional to their climate suitability. Scores all 50 states from 2008–2023 on how well renewable investment aligns with resource potential, benchmarked against 12 countries internationally. Built as an interactive dashboard so the methodology and state-by-state results can be explored directly rather than read as a static report.
Quarto · PostgreSQL · Python · Willamette MS DS Capstone How Job Automatability Relates to County Affordability County level panel study, 2010 to 2023, testing whether occupational task composition predicts cost adjusted housing affordability. Built on a normalized Postgres warehouse of roughly 12,000 county year observations. Co-authored with Chris Bell.
Open to opportunities

Let's build
something.

apacheco26@outlook.com