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this is my...
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  • story
  • experience
  • education
  • research
  • toolkit
  • projects

Biomedical Research · Data Science · Machine Learning

Julian Pacheco

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01

Story

Biomedical researcher with four years in HIV/SIV immunology at OHSU's Vaccine and Gene Therapy Institute, with an MS in Data Science from Willamette University. My work spans human HIV immunology and nonhuman primate SIV models, conducted under the mentorship of Dr. Hiroshi Takata across Dr. Lydie Trautmann's and Dr. Afam Okoye's labs, with recent collaboration with Dr. David Ho's team at Columbia University. My future focus is drug discovery, applying machine learning to accelerate identification of novel therapeutic candidates at the intersection of computational biology and translational medicine.

02

Experience

2021 — Present
Research Assistant
Vaccine and Gene Therapy Institute · OHSU · Beaverton, OR
  • Contributed immune response analysis to a Phase 1b trial of lenacapavir, an FDA Breakthrough Therapy designated regimen now in Phase 2, joining a collaborative effort to bring this lifesaving treatment closer to market.
  • Built and ran multiparameter flow cytometry pipelines across human and NHP models, transforming high dimensional data into quantified results that anchored publications, presentations, and grant reporting.
  • Contributed to a multidisciplinary team designing longitudinal NHP and human studies, building time series data structures (viral load, cytokine, cell associated RNA/DNA) from in vivo and in vitro samples to study how SIV and HIV persist during treatment.
2020
Biological Field Technician (Contract)
Bureau of Land Management · via Oregon State University · Lakeview, OR
  • Built rigorous data collection and integrity practices in the field on a Greater Sage Grouse and juniper removal study, the same foundation of clean, reliable data that drives my work from raw inputs to analysis today.
  • Collected precise field data across a diverse range of instruments and methods, from vegetation and soil sampling to radio telemetry, nest assessments, and brood counts, building the technical versatility I carry across tools and platforms today.
03

Education

2024 — 2026
M.S., Data Science
Willamette University · Salem, OR
2017
B.S., Biology
Portland State University · Portland, OR
04

Research & Presentations

2026
Takata H, Pacheco J, et al. “RV550: IL-15 Superagonist N-803 at ART Interruption Enhances NK and T Cell Proliferation and Activation Prior to Viral Rebound.” Contributions featured.
Keystone Symposia — HIV Persistence, Remission, and Cure · Breckenridge, CO
Poster
2025
Cai Y, Takata H, Ferreira AM, Pacheco Mendez J, et al. “HIV-Specific T Cell Responses in Suppressed People with HIV-1 Receiving Lenacapavir, Teropavimab, and Zinlirvimab.” Contributions featured.
IAS 2025, Kigali, Rwanda · #OAA0205
Oral
2025
Takata H, Pacheco J, et al. “RV550: IL-15 Superagonist N-803 With ART in Acute HIV Infection Enhances T and NK Cell Proliferation.” Contributions featured.
CROI 2025, San Francisco, CA · #0444
Poster
2025
Varco-Merth B, Marino A, Takata H, Pacheco J, et al. “IL-15 Superagonist at ART Initiation Expands SIV-Specific CD8+ T Cells in Blood and Lymphoid Tissues.” Contributions featured.
CROI 2025, San Francisco, CA · #309
Poster
2023
Takata H, Mitchell JL, Pacheco J, et al. “An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status.”
Cell Host & Microbe, 31(9):1494–1506.e4
Paper
2023
Mitchell J, Subra C, Julian Pacheco, et al. “Compartmentalized Clonal Expansions of CD8+ T Cells in CSF During Acute HIV Infection.” Contributions featured.
CROI 2023 (Virtual)
Poster
05

Toolkit

Wet Lab & Immunology

  • Multiparameter flow cytometry core
  • Intracellular cytokine staining core
  • CFSE proliferation assays core
  • AIM / ICS assays core
  • Clinical trial sample workflows core

Data & ML

  • Python core
  • PostgreSQL / DuckDB core
  • scikit-learn / XGBoost core
  • TensorFlow in progress
  • R / Shiny core

Engineering

  • Apache Airflow core
  • Docker core
  • Git / CI core
Open to opportunities

Let's build
something.

apacheco26@outlook.com